Effect of Healthy and Tumor-Associated Breast Adipose Tissue on Breast Cancer Cell Migration and Activation
This study shows that breast adipose tissue from healthy women, BRCA1/2 mutation carriers and BC patients, can stimulate BC cell line migration and activation. This effect is related to BC subtype and BMI. These data improve insight in adipose tissue as factor in BC development.
Authors
- Iris L. Holt-Kedde (ORCID: https://orcid.org/0000-0002-0368-2508)
- Marlous Arjaans
- Mieke C. Zwager (ORCID: https://orcid.org/0000-0002-4470-7628)
- Carolien P. Schröder
- Hetty Timmer‐Bosscha
- Frank A. E. Kruyt
- Wendy Kelder
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- The Netherlands Cancer Institute (NL)
- OLVG (NL)
- Martini Ziekenhuis (NL)
Publication Details
- Journal
- Cancers
- Published
- 2026-03-08
- DOI
- https://doi.org/10.3390/cancers18050868
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00