Association between assisted reproductive technology and gestational diabetes mellitus: the role of serum folate and triglycerides

Our study confirms that ART pregnancies are associated with a higher risk of GDM and with elevated circulating folate and triglyceride concentrations at delivery. These findings highlight the importance of monitoring GDM risk and metabolic profiles in pregnancies achieved through ART. Future studies with biomarker assessments earlier in gestation are needed to clarify whether maternal folate and lipid metabolism contribute causally to the excess risk of GDM in ART pregnancies.