Chronic exercise training intensity, immune cells, and cancer outcomes: a scoping review

While direct comparisons of exercise intensities are lacking, these results suggest that vigorous exercise training may exert greater immune modulation than low-to-moderate intensity exercise training. Rigorously designed trials are needed to confirm these findings and establish the role of exercise in oncologic care.

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Publication Details

Journal
JNCI Cancer Spectrum
Published
2026-03-03
DOI
https://doi.org/10.1093/jncics/pkag021
Primary Topic
Exercise and Physiological Responses
Type
article
Field-Weighted Citation Impact
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article

Chronic exercise training intensity, immune cells, and cancer outcomes: a scoping review

Keri Schadler, Emily C. LaVoy, Maria C. Swartz, José Cesar Rosa Neto et al.
JNCI Cancer Spectrum
Exercise and Physiological Responses
article

Chronic exercise training intensity, immune cells, and cancer outcomes: a scoping review

Keri Schadler, Emily C. LaVoy, Maria C. Swartz, José Cesar Rosa Neto, Saman Maleki Vareki, Kerry S Courneya, Dong-Woo Kang, Nancy B Gordon, Richard J Simpson, K Scott Baker
article en

Abstract

While direct comparisons of exercise intensities are lacking, these results suggest that vigorous exercise training may exert greater immune modulation than low-to-moderate intensity exercise training. Rigorously designed trials are needed to confirm these findings and establish the role of exercise in oncologic care.

JNCI Cancer SpectrumVol. 10(2)
Western University (CA), The University of Texas MD Anderson Cancer Center (US), University of Arizona (US), University of Alberta (CA), Universidade de São Paulo (BR), Fred Hutch Cancer Center (US), Houston Health and Human Services Department (US), University of Houston (US), The University of Texas Medical Branch at Galveston (US)
Good health and well-being
Openalex Percentile: Top 30%
Exercise and Physiological Responses
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Chronic exercise training intensity, immune cells, and cancer outcomes: a scoping review — Keri Schadler, Emily C. LaVoy, et al. · JNCI Cancer Spectrum (2026) | TGRS Research Map | TGRS