Unusual experiences and early-onset psychosis associated to hallucinogen use in adolescents: a systematic review and meta-analysis
Hallucinogen use is common in adolescents with EOP and seems to be associated with more complex clinical trajectories, particularly higher rates of suicidality. Although not an isolated causal trigger, hallucinogens may contribute to symptom exacerbation in neurodevelopmentally or genetically predisposed youth. Future research should prioritise longitudinal, large-scale studies and introduce clinical trials in the field.
Authors
- Eleonora Armyra
- Clàudia Aymerich (ORCID: https://orcid.org/0000-0003-0040-1608)
- Borja Pedruzo (ORCID: https://orcid.org/0000-0003-1460-1571)
- Miguel Angel Gonzalez-Torres
- Gonzalo Salazar de Pablo
- Alazne Ramírez
- Maite Armanino-Irigaray
- Ignacio Argüelles
- Ana Catalán
Institutions
- University of the Basque Country (ES)
- King's College London (GB)
- South London and Maudsley NHS Foundation Trust (GB)
- Hospital General Universitario Gregorio Marañón (ES)
- BioCruces Health research Institute (ES)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Hospital de Basurto (ES)
- Achucarro Basque Center for Neuroscience (ES)
Publication Details
- Journal
- Child and Adolescent Psychiatry and Mental Health
- Published
- 2026-03-08
- DOI
- https://doi.org/10.1186/s13034-026-01060-1
- Primary Topic
- Psychedelics and Drug Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00