A Phase 1 Prognostic Trial for Predicting Paediatric Allergy Using the Placenta at Birth
This study demonstrates that placental glucocorticoid-regulated genes possess significant predictive power, especially in identifying individuals unlikely to develop allergies. It offers further evidence that the placentae of nonallergic children and allergic children are transcriptionally distinct.
Authors
- Sailesh I.S. Kumar (ORCID: https://orcid.org/0000-0003-0832-4811)
- Jane Peake (ORCID: https://orcid.org/0000-0001-9003-5861)
- Zarqa Saif (ORCID: https://orcid.org/0000-0002-2916-1428)
- Andrew W. Tai (ORCID: https://orcid.org/0000-0002-6877-450X)
- BIS Investigator Group
- Ana Patricia Balbon
- Peter D. Sly (ORCID: https://orcid.org/0000-0001-6305-2201)
- Richard R.S. Saffery
- JR Davies
- Vicki L. Clifton
- Peter J. Vuillermin
- Muhammad Afnan
- Brian Cox
Institutions
- Barwon Health (AU)
- Royal Children's Hospital (AU)
- Children's Medical Research Institute (AU)
- Queensland University of Technology (AU)
- The University of Queensland (AU)
- University of Toronto (CA)
- Women's and Children's Hospital (AU)
- Children’s Health Queensland Hospital and Health Service (AU)
- Mater Research (AU)
- Murdoch Children's Research Institute (AU)
- Children's Health Queensland Hospital and Health Service (AU)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2026-03-07
- DOI
- https://doi.org/10.1111/cea.70272
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00