Clinical features, prognosis, and influencing factors of relapse in autoimmune encephalitis associated with antibodies against cell surface antigens: a single-center retrospective study

AEASA subtypes differ significantly in demographic characteristics, clinical manifestations, laboratory results, and imaging findings, forming distinct disease spectra. Hospital stay duration, CRP, and CAR are robust, independent biomarkers for predicting poor prognosis in AEASA patients, providing important guidance for clinical risk stratification and treatment decisions. Early identification and intervention for high-risk patients with relapse potential are crucial for improving long-term prognosis.

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Publication Details

Journal
European journal of medical research
Published
2026-03-08
DOI
https://doi.org/10.1186/s40001-026-04111-7
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
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article

Clinical features, prognosis, and influencing factors of relapse in autoimmune encephalitis associated with antibodies against cell surface antigens: a single-center retrospective study

Zhenhai Wang, Jing Zhou, Yixin Gu, pankui Li
European journal of medical research
Autoimmune Neurological Disorders and Treatments
article

Clinical features, prognosis, and influencing factors of relapse in autoimmune encephalitis associated with antibodies against cell surface antigens: a single-center retrospective study

Zhenhai Wang, Jing Zhou, Yixin Gu, pankui Li
article en

Abstract

AEASA subtypes differ significantly in demographic characteristics, clinical manifestations, laboratory results, and imaging findings, forming distinct disease spectra. Hospital stay duration, CRP, and CAR are robust, independent biomarkers for predicting poor prognosis in AEASA patients, providing important guidance for clinical risk stratification and treatment decisions. Early identification and intervention for high-risk patients with relapse potential are crucial for improving long-term prognosis.

European journal of medical research
Union Hospital (HK), Northwest Institute of Mining and Metallurgy (CN), Ningxia Seismological Bureau (CN), Ningxia Medical University (CN), Ningxia Medical University General Hospital (CN), The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
No poverty
Openalex Percentile: Top 36%
Autoimmune Neurological Disorders and Treatments
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Clinical features, prognosis, and influencing factors of relapse in autoimmune encephalitis associated with antibodies against cell surface antigens: a single-center retrospective study — Zhenhai Wang, Jing Zhou, et al. · European journal of medical research (2026) | TGRS Research Map | TGRS