Hyaluronic acid-based reduction responsive nanoparticles for Improved anti-psoriasis effects of traditional Chinese herb monomer oleanolic acid via blocking YAP-AREG axis
OA-NPs@OA represents a novel targeted nanotherapy that overcomes the limitations of OA in anti-psoriasis by offering enhanced bioavailability, multimodal anti-psoriatic action, and optimized safety profiles.
Authors
- Bo Li (ORCID: https://orcid.org/0000-0002-6129-321X)
- Yan Su (ORCID: https://orcid.org/0000-0003-3970-3822)
- Ying Han (ORCID: https://orcid.org/0000-0002-8381-4071)
- Fei Kong (ORCID: https://orcid.org/0000-0002-2029-8014)
- Guolin Li
- Xinyuan Zhu
- Junjie Ren
- Linzhu Zhou
Institutions
- Jiamusi University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Eighth People Hospital (CN)
- Chemical Synthesis Lab (SG)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2026-03-08
- DOI
- https://doi.org/10.1186/s12951-026-04264-x
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00