IMMT downregulation promotes osteoarthritis development by inducing mitochondrial dysfunction
The identified DE-MRG signature holds significant potential for predicting OA. The downregulation of IMMT may contribute to OA pathogenesis by inducing mitochondrial dysfunction. These findings provide a foundation for developing more effective diagnostic and therapeutic strategies for OA.
Authors
- Lvlin Yang (ORCID: https://orcid.org/0000-0002-9029-7842)
- Jianjun Wang (ORCID: https://orcid.org/0000-0001-7039-7136)
- Binyang Wang
- Qing Ma (ORCID: https://orcid.org/0000-0001-8255-2308)
- Yinghao Cheng
Institutions
- Ningxia Hui Autonomous Region Peoples Hospital (CN)
- Ningxia Medical University (CN)
- The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2026-03-08
- DOI
- https://doi.org/10.1186/s13018-026-06775-7
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00