Evaluation of IVIM-MRI biomarkers for microvascular dysfunction and prognosis in juvenile osteochondritis dissecans of the knee: a single-center study

IVIM-MRI provides quantitative, non-invasive biomarkers that sensitively characterize microvascular compromise in JOCD and support objective assessment of lesion stability. The prognostic utility of these biomarkers for clinical outcomes, however, remains uncertain and warrants validation in prospective studies with arthroscopic ground truth (ROCK classification) and longitudinal follow-up.

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Publication Details

Journal
Journal of Orthopaedic Surgery and Research
Published
2026-03-08
DOI
https://doi.org/10.1186/s13018-026-06774-8
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
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article

Evaluation of IVIM-MRI biomarkers for microvascular dysfunction and prognosis in juvenile osteochondritis dissecans of the knee: a single-center study

Fatih Emre Topsakal, Esra Demirel, Hüseyin Utku Özdeş, Nasuhi Altay et al.
Journal of Orthopaedic Surgery and Research
Osteoarthritis Treatment and Mechanisms
article

Evaluation of IVIM-MRI biomarkers for microvascular dysfunction and prognosis in juvenile osteochondritis dissecans of the knee: a single-center study

Fatih Emre Topsakal, Esra Demirel, Hüseyin Utku Özdeş, Nasuhi Altay, Ekrem Özdemir, Mümin Karahan
article en

Abstract

IVIM-MRI provides quantitative, non-invasive biomarkers that sensitively characterize microvascular compromise in JOCD and support objective assessment of lesion stability. The prognostic utility of these biomarkers for clinical outcomes, however, remains uncertain and warrants validation in prospective studies with arthroscopic ground truth (ROCK classification) and longitudinal follow-up.

Journal of Orthopaedic Surgery and Research
Kafkas University (TR), Inonu University (TR), Erzurum Regional Training and Research Hospital (TR)
Reduced inequalities
Openalex Percentile: Top 28%
Osteoarthritis Treatment and Mechanisms
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