Infiltrated Facial Plaques With 40‐Year Evolution

An elderly woman presented with a chronic, infiltrative plaque on the nasal dorsum and malar region, persisting for decades. Histopathology revealed a granulomatous process, but the etiology remained uncertain despite extensive investigation. This case illustrates the diagnostic challenge of a slowly progressive facial plaque with tuberculoid granulomas and negative microbiological special stains, highlighting the importance of clinicopathological correlation and follow-up in endemic areas for chronic granulomatous dermatoses.

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Publication Details

Journal
International Journal of Dermatology
Published
2026-03-07
DOI
https://doi.org/10.1111/ijd.70377
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Infiltrated Facial Plaques With 40‐Year Evolution

Andreia Akina Akamine, Helena Zenedin Marchioro, Maiara Christine Macagnan
International Journal of Dermatology
Autoimmune and Inflammatory Disorders
article

Infiltrated Facial Plaques With 40‐Year Evolution

Andreia Akina Akamine, Helena Zenedin Marchioro, Maiara Christine Macagnan
article en

Abstract

An elderly woman presented with a chronic, infiltrative plaque on the nasal dorsum and malar region, persisting for decades. Histopathology revealed a granulomatous process, but the etiology remained uncertain despite extensive investigation. This case illustrates the diagnostic challenge of a slowly progressive facial plaque with tuberculoid granulomas and negative microbiological special stains, highlighting the importance of clinicopathological correlation and follow-up in endemic areas for chronic granulomatous dermatoses.

International Journal of Dermatology
Instituto de Neurologia de Curitiba (BR)
Gender equality
Openalex Percentile: Top 31%
Autoimmune and Inflammatory Disorders
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