Identification and assessment of paediatric cefepime-induced neurotoxicity in a retrospective cohort of paediatric intensive care patients
This investigation presents a paediatric cohort analysis of CIN and provides preliminary evidence supporting the hypothesis that neurotoxicity risk is probably concentration dependent in this age group and presents with similar spectrum of symptoms as those described in adults.
Authors
- Kelli Paice (ORCID: https://orcid.org/0000-0003-0863-7316)
- Jennifer Kaplan (ORCID: https://orcid.org/0000-0001-7020-2394)
- Kathryn Pavia (ORCID: https://orcid.org/0000-0002-6231-3323)
- Melissa E Day (ORCID: https://orcid.org/0000-0002-2131-0177)
- M. Fenchel
- Anna Jane Sibilia
- Sonya Tang Girdwood
- H Rhodes Hambrick
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1093/jac/dkag075
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00