Direct‐stick embolization to treat hematochezia secondary to rectally metastatic sacral neuroblastoma

Abstract Neuroblastoma is a malignant tumor that is typically treated with a combination of surgery, radiation therapy, chemotherapy, and immunotherapy. However, minimally invasive embolization and chemoembolization present promising new treatment modalities. We present the case of a 6‐year‐old patient who initially presented with a massive lower GI bleed due to sacral neuroblastoma metastasis invading the rectum, that was managed via transarterial embolization and transrectal endoscopic‐guided percutaneous nBCA embolization. There was significant tumoral supply from the posterior division of the internal iliac arteries treated with coil, liquid, and particle embolics. Subsequently, under endoscopic guidance, liquid embolization via direct puncture of the rectal metastasis was performed to manage any residual vascularity. Thereafter, the patient's lower GI bleed resolved. Direct puncture tumoral embolization offers a potentially highly effective, yet minimally invasive procedure that warrants further evaluation.

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Publication Details

Journal
JPGN Reports
Published
2026-02-26
DOI
https://doi.org/10.1002/jpr3.70160
Primary Topic
Neuroblastoma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Direct‐stick embolization to treat hematochezia secondary to rectally metastatic sacral neuroblastoma

Collin Barker, Ravjot Dhatt, Manraj K. S. Heran, Leandro Cardarelli‐Leite et al.
JPGN Reports
Neuroblastoma Research and Treatments
article

Direct‐stick embolization to treat hematochezia secondary to rectally metastatic sacral neuroblastoma

Collin Barker, Ravjot Dhatt, Manraj K. S. Heran, Leandro Cardarelli‐Leite, Anand Dhatt
article en

Abstract

Abstract Neuroblastoma is a malignant tumor that is typically treated with a combination of surgery, radiation therapy, chemotherapy, and immunotherapy. However, minimally invasive embolization and chemoembolization present promising new treatment modalities. We present the case of a 6‐year‐old patient who initially presented with a massive lower GI bleed due to sacral neuroblastoma metastasis invading the rectum, that was managed via transarterial embolization and transrectal endoscopic‐guided percutaneous nBCA embolization. There was significant tumoral supply from the posterior division of the internal iliac arteries treated with coil, liquid, and particle embolics. Subsequently, under endoscopic guidance, liquid embolization via direct puncture of the rectal metastasis was performed to manage any residual vascularity. Thereafter, the patient's lower GI bleed resolved. Direct puncture tumoral embolization offers a potentially highly effective, yet minimally invasive procedure that warrants further evaluation.

JPGN Reports
Western University (CA), Vancouver General Hospital (CA), BC Children's Hospital (CA)
Good health and well-being
Openalex Percentile: Top 36%
Neuroblastoma Research and Treatments
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