Colchicine acutely reduces liver-secreted inflammatory and metabolic proteins in blood
In summary, we have identified that acute colchicine in vivo modulates the serum and plasma proteome of liver-derived components, leading to systemic metabolic and immune changes.
Authors
- Danielle J. Smyth (ORCID: https://orcid.org/0000-0001-6080-2679)
- Alison D. McNeilly (ORCID: https://orcid.org/0000-0003-4869-178X)
- Iain R. Phair (ORCID: https://orcid.org/0000-0001-7814-0263)
- Graham Rena (ORCID: https://orcid.org/0000-0002-9121-1350)
- Erika J. Gutiérrez-Lara (ORCID: https://orcid.org/0000-0003-1780-7487)
- Raid B. Nisr
- Magdalena Sovakova
- Douglas Lamont
- Noor Alqurashi
- Claire Whyte
- H McSorley
- Sean Yap
- Nicola J. Mutch
Institutions
- University of Dundee (GB)
- University of Aberdeen (GB)
Publication Details
- Journal
- European Journal of Pharmacology
- Published
- 2026-03-07
- DOI
- https://doi.org/10.1016/j.ejphar.2026.178725
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00