Ocular biometry agreement among ZW-30, IOLMaster 700, and sirius in cataract patients

Accurate ocular biometry is crucial for the success of refractive cataract surgery. This study aims to assess the consistency and differences of a new biometer, the ZW-30, compared with the mainstream devices IOLMaster 700 and Sirius in patients with cataracts. A total of 307 patients with cataracts (603 eyes) were included. The anterior chamber depth (ACD), central corneal thickness (CCT), white-to-white (WTW) distance, pupil diameter (PD), flat K (K1), steep K (K2), corneal astigmatism (ΔK), total keratometry (TK), total corneal astigmatism (TCA), astigmatism axis, kappa angle (κ), axial length (AL), and lens thickness (LT) were measured using the ZW-30, IOLMaster 700, and Sirius. The consistency between devices was evaluated using Bland-Altman analysis, the correlation of parameters was assessed using Spearman correlation analysis, and inter-device agreement equations were established. Strong correlations (r ≥ 0.7) and no statistically significant differences in mean values (p > 0.05) were found for ACD, CCT, AL, LT, and anterior corneal curvature (K1/K2) among the three devices, but the 95% limits of agreement (LoA) exceeded the clinical threshold. Total corneal parameters (TK/TCA) and κ angle showed strong correlations (r ≥ 0.5) among the three devices, with significant inter-device differences in mean values (p < 0.05) and 95%LoA exceeding the clinical threshold. Corneal diameter (WTW) had a weak correlation (r = 0.48) between the ZW-30 and Sirius, and differences in PD measurement methods led to systematic bias. The ZW-30 is consistent with the IOLMaster 700 and Sirius in terms of group trends for basic biometric parameters (ACD/CCT/anterior corneal curvature), but significant individual differences exist (95%LoA exceeding the threshold). Total corneal parameters (TK/TCA) and κ angle require cross-validation with Sirius. WTW and PD are not interchangeable between devices due to differences in measurement principles. Cross-device parameter conversion should be avoided in clinical practice to ensure the accuracy of refractive surgery.

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Journal
Scientific Reports
Published
2026-03-08
DOI
https://doi.org/10.1038/s41598-026-42451-w
Primary Topic
Intraocular Surgery and Lenses
Type
article
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article

Ocular biometry agreement among ZW-30, IOLMaster 700, and sirius in cataract patients

YuKan Huang, Nijuan Yang, Xuan Yu, Ling Jin et al.
Scientific Reports
Intraocular Surgery and Lenses
article

Ocular biometry agreement among ZW-30, IOLMaster 700, and sirius in cataract patients

YuKan Huang, Nijuan Yang, Xuan Yu, Ling Jin, Junjie Yang, Yuying Xiang, Rui Li
article en

Abstract

Accurate ocular biometry is crucial for the success of refractive cataract surgery. This study aims to assess the consistency and differences of a new biometer, the ZW-30, compared with the mainstream devices IOLMaster 700 and Sirius in patients with cataracts. A total of 307 patients with cataracts (603 eyes) were included. The anterior chamber depth (ACD), central corneal thickness (CCT), white-to-white (WTW) distance, pupil diameter (PD), flat K (K1), steep K (K2), corneal astigmatism (ΔK), total keratometry (TK), total corneal astigmatism (TCA), astigmatism axis, kappa angle (κ), axial length (AL), and lens thickness (LT) were measured using the ZW-30, IOLMaster 700, and Sirius. The consistency between devices was evaluated using Bland-Altman analysis, the correlation of parameters was assessed using Spearman correlation analysis, and inter-device agreement equations were established. Strong correlations (r ≥ 0.7) and no statistically significant differences in mean values (p > 0.05) were found for ACD, CCT, AL, LT, and anterior corneal curvature (K1/K2) among the three devices, but the 95% limits of agreement (LoA) exceeded the clinical threshold. Total corneal parameters (TK/TCA) and κ angle showed strong correlations (r ≥ 0.5) among the three devices, with significant inter-device differences in mean values (p < 0.05) and 95%LoA exceeding the clinical threshold. Corneal diameter (WTW) had a weak correlation (r = 0.48) between the ZW-30 and Sirius, and differences in PD measurement methods led to systematic bias. The ZW-30 is consistent with the IOLMaster 700 and Sirius in terms of group trends for basic biometric parameters (ACD/CCT/anterior corneal curvature), but significant individual differences exist (95%LoA exceeding the threshold). Total corneal parameters (TK/TCA) and κ angle require cross-validation with Sirius. WTW and PD are not interchangeable between devices due to differences in measurement principles. Cross-device parameter conversion should be avoided in clinical practice to ensure the accuracy of refractive surgery.

Scientific Reports
Union Hospital (HK), Wuhan Union Hospital (CN), Union Hospital (CN), Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 30%
Intraocular Surgery and Lenses
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