Offline Reconstruction of Diffusion <scp>MRI</scp> Acquisitions for Comparison Between Complex <scp>PCA</scp> ‐Based and <scp>AI</scp> ‐Based Denoising

We found significant gains in dMRI data quality when using the proposed offline reconstruction pipeline, allowing complex-domain denoising to obtain high-quality data at high spatial resolution and b-value, using a wide-bore scanner and a standard PGSE EPI sequence. MPPCA<sub>SVS</sub> and NORDIC (4D PCA-based) outperformed ARDL (2D) in terms of spatial resolution and reduction of noise variance.

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Publication Details

Journal
Magnetic Resonance in Medicine
Published
2026-03-07
DOI
https://doi.org/10.1002/mrm.70336
Primary Topic
Advanced Neuroimaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Offline Reconstruction of Diffusion MRI Acquisitions for Comparison Between Complex PCA ‐Based and AI ‐Based Denoising

Shaun Warrington, Stamatios N. Sotiropoulos, Paul S. Morgan, Francesco D'Antonio et al.
Magnetic Resonance in Medicine
Advanced Neuroimaging Techniques and Applications
article

Offline Reconstruction of Diffusion MRI Acquisitions for Comparison Between Complex PCA ‐Based and AI ‐Based Denoising

Shaun Warrington, Stamatios N. Sotiropoulos, Paul S. Morgan, Francesco D'Antonio, Jose‐Pedro Manzano‐Patron
article en

Abstract

We found significant gains in dMRI data quality when using the proposed offline reconstruction pipeline, allowing complex-domain denoising to obtain high-quality data at high spatial resolution and b-value, using a wide-bore scanner and a standard PGSE EPI sequence. MPPCA<sub>SVS</sub> and NORDIC (4D PCA-based) outperformed ARDL (2D) in terms of spatial resolution and reduction of noise variance.

Magnetic Resonance in Medicine
University of Nottingham (GB), Institute of Mental Health (GB), Nottingham Biomedical Research Centre (GB)
Openalex Percentile: Top 31%
Advanced Neuroimaging Techniques and Applications
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Offline Reconstruction of Diffusion <scp>MRI</scp> Acquisitions for Comparison Between Complex <scp>PCA</scp> ‐Based and <scp>AI</scp> ‐Based Denoising — Shaun Warrington, Stamatios N. Sotiropoulos, et al. · Magnetic Resonance in Medicine (2026) | TGRS Research Map | TGRS