Multi-omics analysis reveals Yishen Qutong formula promotes ferroptosis in Lewis lung cancer associated with Keap1/Nrf2/Nqo1 pathway modulation
YSQTF promoted ferroptosis in Lewis lung cancer, which was associated with the Keap1/Nrf2/Nqo1 pathway. 3-hydroxycinnamic acid might be a serum component in YSQTF regulating the expression of Keap1.
Authors
- Sujuan Zheng
- Yijing Yan
- Jingjie Yu
- Sicong Li (ORCID: https://orcid.org/0000-0002-6414-6645)
- Yue Jin
- Yiyuan Cui
- Li Feng
- Yi Li
- Yufan Chen
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2026-03-07
- DOI
- https://doi.org/10.1016/j.jep.2026.121469
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00