Evaluation of serum irisin and meteorin‐like ( <scp>METRNL</scp> ) levels in people with drug‐resistant and drug‐responsive temporal lobe epilepsy
Serum METRNL levels are significantly reduced in people with TLE regardless of drug resistance, whereas irisin levels remain unchanged. The reduction in METRNL may reflect underlying neuroinflammatory or metabolic dysfunctions associated with epilepsy. Given the association between physical activity and METRNL, lifestyle interventions may offer therapeutic potential. METRNL warrants further investigation as a candidate biomarker for TLE.
Authors
- Füsun Ferda Erdoğan (ORCID: https://orcid.org/0000-0002-6315-7529)
- Şeyma Benli (ORCID: https://orcid.org/0000-0001-5110-9768)
- didem barlak keti
- EsraNur KAYA
- Ravza Tosunbayraktar (ORCID: https://orcid.org/0000-0001-5590-5016)
- Can Kog
Institutions
- Koç University (TR)
- Kahramanmaraş Sütçü İmam University (TR)
- Erciyes University (TR)
Publication Details
- Journal
- Epileptic Disorders
- Published
- 2026-03-08
- DOI
- https://doi.org/10.1002/epd2.70212
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00