Functional investigation of the <scp> <i>RHD</i> </scp> gene promoter: Molecular changes are rarely responsible for variant D phenotype in Thai donors

Regulation of RH gene expression is likely to involve other levels of complexity that remain to be identified. Future investigations are necessary to characterize those critical genomic regions that potentially carry rare variants responsible for weakening or abolishment of D antigen expression.

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Publication Details

Journal
Transfusion
Published
2026-03-07
DOI
https://doi.org/10.1111/trf.70155
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
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article

Functional investigation of the RHD gene promoter: Molecular changes are rarely responsible for variant D phenotype in Thai donors

Yann Fichou, Pornlada Nuchnoi
Transfusion
Blood groups and transfusion
article

Functional investigation of the RHD gene promoter: Molecular changes are rarely responsible for variant D phenotype in Thai donors

Yann Fichou, Pornlada Nuchnoi
article en

Abstract

Regulation of RH gene expression is likely to involve other levels of complexity that remain to be identified. Future investigations are necessary to characterize those critical genomic regions that potentially carry rare variants responsible for weakening or abolishment of D antigen expression.

Transfusion
Inserm (FR), Université de Bretagne Occidentale (FR), École nationale d'ingénieurs de Brest (FR), Mahidol University (TH), Génétique, Génomique Fonctionnelle et Biotechnologies (FR)
Zero hunger
Openalex Percentile: Top 29%
Blood groups and transfusion
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