Evaluating the performance of ancient DNA genetic relatedness estimation methods using high-fidelity pedigree simulations
The results of this benchmark enable us to discuss the individual strengths and limitations of these methods, propose a set of prescriptions to consider when interpreting their results and demonstrate that their reliability cannot be predicted from sample coverage alone, and may be subject to multiple sources of bias.
Authors
- Marie‐Claude Marsolier
- Céline Bon
- Maël Lefeuvre
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université Paris Cité (FR)
- Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR)
- Université Paris-Saclay (FR)
- Institut de Biologie Intégrative de la Cellule (FR)
- CEA Paris-Saclay (FR)
- Musée de l'Homme (FR)
Publication Details
- Journal
- Genome biology
- Published
- 2026-03-09
- DOI
- https://doi.org/10.1186/s13059-026-04016-y
- Primary Topic
- Forensic and Genetic Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00