Novel cinnamic acid derivatives enable the induction of chloroplast‐associated immunity and interaction with viral coat proteins for plant viral disease control
This study identifies B<sub>7</sub> as the optimal antiviral agent with superior efficacy and biosafety, defines critical structure-activity relationship principles governing cinnamic acid-based antiviral agent design, and mechanistically validates its dual-action mechanisms involving chloroplast-potentiated systemic immunity and direct TMV-CP interactions. It provides an important reference for the development of efficient and multitarget antiviral agents. © 2026 Society of Chemical Industry.
Authors
- Heng Zhang (ORCID: https://orcid.org/0000-0002-0103-2173)
- Xia Zhou (ORCID: https://orcid.org/0000-0002-4037-6809)
- Rong‐Shuang Luo
- Yong Huang (ORCID: https://orcid.org/0000-0001-8377-8923)
- Yu‐Cheng Gu
- Hong‐Mei Xiang
- Xiang‐Xu Zhou
- Song Yang
- Dan Zeng
- Wu‐Bin Shao
- Guo Wang
Institutions
- Guizhou University (CN)
- Syngenta (United Kingdom) (GB)
- Qiannan Normal College For Nationalities (CN)
Publication Details
- Journal
- Pest Management Science
- Published
- 2026-03-07
- DOI
- https://doi.org/10.1002/ps.70703
- Primary Topic
- Plant Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00