Medication use during pregnancy in Japan from 2005 to 2019: Trends and safety considerations
A significant proportion of medications commonly dispensed during pregnancy in Japan have inadequate teratogenic safety evidence. Several medication classes showed increasing utilization trends over the study period, emphasizing the urgent need for targeted safety evaluations in the Japanese population.
Authors
- Tomofumi Ishikawa (ORCID: https://orcid.org/0000-0002-0901-368X)
- Takamasa Sakai (ORCID: https://orcid.org/0000-0001-9086-6999)
- Motohiko Adomi (ORCID: https://orcid.org/0000-0003-4277-4509)
- Taku Obara
- Krista F. Huybrechts
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Tohoku University (JP)
- Tohoku University Hospital (JP)
- Tohoku Medical Megabank Organization (JP)
- Meijo University (JP)
Publication Details
- Journal
- International Journal of Gynecology & Obstetrics
- Published
- 2026-03-07
- DOI
- https://doi.org/10.1002/ijgo.70860
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00