Ferroptosis mediates retinal damage caused by the combined effects of sleep deprivation and light damage
Short-term sleep deprivation exacerbated light-induced retinal injury by promoting ferroptosis, as indicated by disrupted antioxidant capacity, enhanced lipid peroxidation, and disturbed iron homeostasis. Treatment with Lip-1 substantially attenuated these changes.
Authors
- Weiting Peng
- Youwen Zhang (ORCID: https://orcid.org/0000-0002-0957-4276)
- Yuting Cai (ORCID: https://orcid.org/0000-0003-2527-9151)
- Yuxian Zou
- Yun Li
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Free Radical Biology and Medicine
- Published
- 2026-03-07
- DOI
- https://doi.org/10.1016/j.freeradbiomed.2026.03.015
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00