Promoting clinical trials in pediatric IgA nephropathy through extrapolation: an artificial intelligence–enhanced literature review of the disease in pediatrics sponsored by the Kidney Health Initiative
In conjunction with the similar biological basis of the disease in pediatric and adult patients, these findings may enable the use of extrapolation in the design of clinical trials in pediatric patients with IgAN.
Authors
- R. Komers
- Lokesh Shah (ORCID: https://orcid.org/0000-0002-8811-9617)
- Nicholas J.A. Webb (ORCID: https://orcid.org/0000-0001-8572-5446)
- Sai Prasad N. Iyer (ORCID: https://orcid.org/0000-0003-0544-7904)
- Cecile Fajardo
- Grace Squillaci
- Eleanor M. Kerr (ORCID: https://orcid.org/0000-0001-9390-4655)
- Raoul D. Nelson
- Xuhui Zhong
- Mark David Lim (ORCID: https://orcid.org/0000-0002-6036-467X)
- Barbara S. Gillespie
- Bonnie Schneider
- Myda Khalid
- Jun Oh
- Howard Trachtman
- Koichi Nakanishi
Institutions
- OncoMed (United States) (US)
- Universität Hamburg (DE)
- Peking University (CN)
- University of Utah (US)
- University of Michigan (US)
- Riley Hospital for Children (US)
- University of the Ryukyus (JP)
- Otsuka (United States) (US)
- Arkana Laboratories (US)
- University Medical Center Hamburg-Eppendorf (DE)
- Indiana University Bloomington (US)
- Peking University First Hospital (CN)
- Women's Health Initiative (US)
- Ripple (United States) (US)
- Fate Therapeutics (United States) (US)
- Swedish Orphan Biovitrum (Switzerland) (CH)
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- Pediatric Nephrology
- Published
- 2026-03-08
- DOI
- https://doi.org/10.1007/s00467-026-07245-2
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00