The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy ( <scp>OMEGA</scp> ) study: Geographic atrophy progression in fundus autofluorescence ‐ <scp>OMEGA</scp> report 3

GA progression in AMD is significantly influenced by baseline lesion size and a larger number of smoking pack-years is associated with larger GA lesions. The marked variability between individuals underscores the multifactorial nature of GA dynamics. Quantitative FAF analysis is a reliable method for assessing lesion progression and may inform risk-based monitoring strategies.

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Publication Details

Journal
Acta Ophthalmologica
Published
2026-03-08
DOI
https://doi.org/10.1111/aos.70119
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy ( OMEGA ) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Faady Yahya, Philippe Valmaggia, Georg Ansari, Hanna Camenzind Zuche et al.
Acta Ophthalmologica
Retinal Diseases and Treatments
article

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy ( OMEGA ) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Faady Yahya, Philippe Valmaggia, Georg Ansari, Hanna Camenzind Zuche, Hendrik P. N. Scholl, Marieh Esmaeelpour, Marco Cattaneo, Peter M. Maloca, Nadja Inglin, Chrysoula Gabrani, Christian Prünte, Taffeta Chingning Yamaguchi, Maximilian Pfau, Nicolas Feltgen, Leopold Schmetterer, Andrea Giani, Nils Schärer
article en

Abstract

GA progression in AMD is significantly influenced by baseline lesion size and a larger number of smoking pack-years is associated with larger GA lesions. The marked variability between individuals underscores the multifactorial nature of GA dynamics. Quantitative FAF analysis is a reliable method for assessing lesion progression and may inform risk-based monitoring strategies.

Acta Ophthalmologica
Moorfields Eye Hospital NHS Foundation Trust (GB), Boehringer Ingelheim (Germany) (DE), University of Basel (CH), Singapore National Eye Center (SG), University Hospital of Basel (CH), Hirslanden Klinik Im Park (CH), Advanced Digital Sciences Center (SG), Singapore Eye Research Institute (SG), Duke-NUS Medical School (SG), Moorfields Eye Hospital (GB), Institute of Molecular and Clinical Ophthalmology Basel (CH), Spitalzentrum Centre hospitalier Biel- Bienne (CH), University College London (GB), Medical University of Vienna (AT), EU Business School, Geneva (CH)
Openalex Percentile: Top 30%
Retinal Diseases and Treatments
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