Cervical intradural‐extramedullary ganglioneuroma in a dog

Abstract This case report describes an intradural‐extramedullary spinal ganglioneuroma in a 4‐year‐old French bulldog with a 2‐month history of cervical hyperaesthesia. Magnetic resonance imaging revealed a well‐defined dorsolateral intradural‐extramedullary lesion at C1–C2, T2‐weighted hyperintense and T1‐weighted hypointense. On computed tomography, it was iso‐ to hypoattenuating. Both imaging modalities demonstrated marked contrast enhancement. Subtotal surgical resection was performed. Histopathological and immunohistochemical analyses were compatible with ganglioneuroma. The dog recovered uneventfully. Follow‐up magnetic resonance imaging at 7 months showed mild tumour remanence and possible slow regrowth, without neurological deficits. Nine months postoperatively, the dog remains neurologically normal. This is the first report of an intradural‐extramedullary cervical spinal ganglioneuroma in a dog, including its magnetic resonance imaging, computed tomography and immunohistochemical features. While uncommon, spinal ganglioneuroma should be considered in the differential diagnosis for lesions with these imaging characteristics. Surgical excision, even when subtotal, is associated with a favourable short‐ and long‐term outcome.

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Publication Details

Journal
Veterinary Record Case Reports
Published
2026-03-02
DOI
https://doi.org/10.1002/vrc2.70387
Primary Topic
Neuroblastoma Research and Treatments
Type
article
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article

Cervical intradural‐extramedullary ganglioneuroma in a dog

Rocio Orlandi, Pablo Amengual, A. Herrmann, Simone Spinillo et al.
Veterinary Record Case Reports
Neuroblastoma Research and Treatments
article

Cervical intradural‐extramedullary ganglioneuroma in a dog

Rocio Orlandi, Pablo Amengual, A. Herrmann, Simone Spinillo, Luis Villalonga
article en

Abstract

Abstract This case report describes an intradural‐extramedullary spinal ganglioneuroma in a 4‐year‐old French bulldog with a 2‐month history of cervical hyperaesthesia. Magnetic resonance imaging revealed a well‐defined dorsolateral intradural‐extramedullary lesion at C1–C2, T2‐weighted hyperintense and T1‐weighted hypointense. On computed tomography, it was iso‐ to hypoattenuating. Both imaging modalities demonstrated marked contrast enhancement. Subtotal surgical resection was performed. Histopathological and immunohistochemical analyses were compatible with ganglioneuroma. The dog recovered uneventfully. Follow‐up magnetic resonance imaging at 7 months showed mild tumour remanence and possible slow regrowth, without neurological deficits. Nine months postoperatively, the dog remains neurologically normal. This is the first report of an intradural‐extramedullary cervical spinal ganglioneuroma in a dog, including its magnetic resonance imaging, computed tomography and immunohistochemical features. While uncommon, spinal ganglioneuroma should be considered in the differential diagnosis for lesions with these imaging characteristics. Surgical excision, even when subtotal, is associated with a favourable short‐ and long‐term outcome.

Veterinary Record Case ReportsVol. 14(2)
At Bristol (GB), Bristol Clinical Commissioning Group (GB), Willows Veterinary Centre and Referral Service (GB)
Openalex Percentile: Top 37%
Neuroblastoma Research and Treatments
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