Synthesis of Dibenzo‐1,2,3‐Triazole Fused 14‐Membered Oxa‐Ketone Macrocycles via Azide‐Alkyne Cycloaddition
ABSTRACT We have successfully synthesized for the first time a series of dibenzo‐1,2,3‐triazole fused 14‐membered oxa‐ketone macrocycles 9a‐j in (61%–92%) yields, from cross‐aldol precursors (1 E ,4 E )‐1‐(2‐azidophenyl)‐5‐(alkyl‐2/6‐(prop‐2‐yn‐1‐yloxy)aryl)penta‐1,4‐dien‐3‐ones 8a‐j , by employing Cu(I)/Ag(I)‐ catalyzed azide‐alkyne cycloaddition reactions.
Authors
- Nasrin Jahan (ORCID: https://orcid.org/0000-0002-3050-7318)
- Inul Ansary (ORCID: https://orcid.org/0000-0001-7745-0833)
- Somasri Dam (ORCID: https://orcid.org/0000-0002-9055-3412)
- Rajlakshmi Laha
- Eman Ali Sk
- Arijit Das
Institutions
- Indian Institute of Technology Guwahati (IN)
- University of Burdwan (IN)
Publication Details
- Journal
- Journal of Heterocyclic Chemistry
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1002/jhet.70180
- Primary Topic
- Click Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00