Outcomes of multigene panel testing for hereditary cancer in two Israeli medical centers 2013–2024

The yield of MGPT in Israel, after exclusion of predominant founder PSVs, was modest. The identification of recurring PSVs warrants further investigation and potential inclusion in updated first-pass genotyping schemes.

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Publication Details

Journal
Cancer Genetics
Published
2026-03-07
DOI
https://doi.org/10.1016/j.cancergen.2026.03.002
Primary Topic
BRCA gene mutations in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Outcomes of multigene panel testing for hereditary cancer in two Israeli medical centers 2013–2024

Iris Netzer, Shelley Zalmanoviz, Eitan Friedman, Yael Laitman et al.
Cancer Genetics
BRCA gene mutations in cancer
article

Outcomes of multigene panel testing for hereditary cancer in two Israeli medical centers 2013–2024

Iris Netzer, Shelley Zalmanoviz, Eitan Friedman, Yael Laitman, Rinat Bernstein-Molho
article en

Abstract

The yield of MGPT in Israel, after exclusion of predominant founder PSVs, was modest. The identification of recurring PSVs warrants further investigation and potential inclusion in updated first-pass genotyping schemes.

Cancer GeneticsVol. 304-305
Sheba Medical Center (IL), Assuta Medical Center (IL)
Reduced inequalities
Openalex Percentile: Top 30%
BRCA gene mutations in cancer
DOIOpen Access PDFOpenAlex
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Outcomes of multigene panel testing for hereditary cancer in two Israeli medical centers 2013–2024 — Iris Netzer, Shelley Zalmanoviz, et al. · Cancer Genetics (2026) | TGRS Research Map | TGRS