A Modular Computational Approach for Assessing Active and Passive Force Contributions in Interstitial Lymphatic Fluid Uptake
Branching topology and material properties fundamentally influence lymphatic drainage. Active pumping is particularly important in highly branched architectures, while interstitial properties mainly modulate passive flow. The framework enables quantitative exploration of regional physiological and pathological differences.
Authors
- Anthony R.J. Phillips (ORCID: https://orcid.org/0000-0001-6143-5866)
- Finbar Argus
- Soroush Safaei (ORCID: https://orcid.org/0000-0001-5734-243X)
- Peter Russell (ORCID: https://orcid.org/0000-0002-7059-6618)
- Hayley M. Reynolds (ORCID: https://orcid.org/0000-0001-8146-1113)
- Tharanga D. Jayathungage Don (ORCID: https://orcid.org/0000-0002-8003-5398)
Institutions
- University of Auckland (NZ)
- Auckland University of Technology (NZ)
Publication Details
- Journal
- Annals of Biomedical Engineering
- Published
- 2026-03-07
- DOI
- https://doi.org/10.1007/s10439-026-04062-4
- Primary Topic
- Lymphatic System and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- New Zealand Government
- European Commission
- Royal Society Te Apārangi
- Ministry of Business, Innovation and Employment
- Universiteit Gent
- Health Research Council of New Zealand
- Marsden Fund