A Comprehensive Study of Interaction between Niacin and Ionic Salts (KCl/MgCl ₂ ) Solutions using Ultrasonic Probe

ABSTRACT In aqueous solutions containing (0.02–0.2) mol‐kg −1 of niacin, densities and sound velocities for salt solutions containing 0.1 m potassium chloride (KCl) and magnesium chloride (MgCl 2 ) have been experimentally calculated at 288 and 298 K temperatures. The following parameters have been determined from this experimental data: isothermal compressibility (kT 1 and kT 2 ), internal pressure (Πi), adiabatic compressibility (β), acoustic impedance (Z), and nonlinear parameter (B/A 1 and B/A 2 ). Niacin and ionic salt play important roles in solute–solvent interactions, as indicated by the changes in these properties with concentration and temperature. To comprehend the numerous interactions inherent in C 6 H 5 NO 2 + KCl/ MgCl 2 aqueous solutions, research in thermodynamics and acoustics was conducted. In this work, hydrogen bonding and solute‐solvent interactions have been emphasized among these interactions, as seen in Scheme 1. Niacin caproate appears to have stronger interactions with the MgCl 2 ionic salt than with the KCl salt solution, based on the volumetric and thermodynamic data. We statistically investigate the structure, anharmonicity, nature, and strength of molecular interactions and structural modifications concerning these binary systems. The solute‐solvent interactions in the vitamin mixes with salt additions are noted to have a major impact on the mixtures' transport and thermodynamic characteristics. These results imply that interactions between niacin and ions such as K + and Mg 2 + may affect physiological processes, including potassium balance and blood pressure management, providing information about possible biomedical uses in treating diseases like hypokalaemia.