Disparities in Lung Cancer Health Outcomes and Access to Lung Cancer Screening Between Rural and Urban Areas in the U.S

Lung cancer is one of the leading causes of mortality in the United States. Despite overall declines in incidence and mortality nationwide, rural communities continue to experience higher rates of lung cancer incidence and mortality than their urban counterparts, a disparity that has persisted over recent decades. This review synthesizes evidence from epidemiologic and clinical studies evaluating rural-urban differences in lung cancer incidence, mortality, diagnostic stage, access to screening, and treatment outcomes. Factors influencing these differences-tobacco use and environmental exposures, socioeconomic inequities, access to healthcare, and psychosocial and spiritual support-are examined as well. The review highlights the importance of increasing access to lung cancer screening and suggests interventions to improve early detection, access to treatment, and enhance psychosocial and spiritual support for patients and caregivers residing in rural areas. In this review, we have followed the urban-rural classification designated by the United States Census Bureau as a rural area consisting of populations, housing, and territory not included within an urban-classified area.

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Publication Details

Journal
Cancers
Published
2026-03-07
DOI
https://doi.org/10.3390/cancers18050864
Primary Topic
Global Cancer Incidence and Screening
Type
article
Field-Weighted Citation Impact
0.00
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article

Disparities in Lung Cancer Health Outcomes and Access to Lung Cancer Screening Between Rural and Urban Areas in the U.S

James Fox, Aishani Gargapati, Erminia Massarelli
Cancers
Global Cancer Incidence and Screening
article

Disparities in Lung Cancer Health Outcomes and Access to Lung Cancer Screening Between Rural and Urban Areas in the U.S

James Fox, Aishani Gargapati, Erminia Massarelli
article en

Abstract

Lung cancer is one of the leading causes of mortality in the United States. Despite overall declines in incidence and mortality nationwide, rural communities continue to experience higher rates of lung cancer incidence and mortality than their urban counterparts, a disparity that has persisted over recent decades. This review synthesizes evidence from epidemiologic and clinical studies evaluating rural-urban differences in lung cancer incidence, mortality, diagnostic stage, access to screening, and treatment outcomes. Factors influencing these differences-tobacco use and environmental exposures, socioeconomic inequities, access to healthcare, and psychosocial and spiritual support-are examined as well. The review highlights the importance of increasing access to lung cancer screening and suggests interventions to improve early detection, access to treatment, and enhance psychosocial and spiritual support for patients and caregivers residing in rural areas. In this review, we have followed the urban-rural classification designated by the United States Census Bureau as a rural area consisting of populations, housing, and territory not included within an urban-classified area.

CancersVol. 18(5)
The University of Texas at Tyler (US)
Good health and well-being
Openalex Percentile: Top 29%
Global Cancer Incidence and Screening
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