Delayed Inflammatory Foreign Body Reaction to PLLA After Genioplasty: A Case Report

ABSTRACT Resorbable plates are widely used in maxillofacial surgery; however, delayed inflammatory foreign body reactions have occasionally been reported. We describe a case of a delayed inflammatory foreign body reaction to poly‐L‐lactic acid (PLLA) resorbable plates following genioplasty. An 18‐year‐old woman underwent genioplasty using PLLA resorbable plates and screws. Approximately 2 years after surgery, she developed progressive swelling and tenderness in the chin region. Computed tomography (CT) revealed localized bone resorption around the fixation device. Surgical removal of the degraded plate remnants, sequestrum, and surrounding inflammatory tissue was performed. Histopathological examination demonstrated granulation tissue containing PLLA fragments with a foreign body giant cell reaction. The postoperative course was uneventful, and bone regeneration was confirmed 1 year after removal. This case highlights that delayed inflammatory foreign body reactions to PLLA plates can occur years after genioplasty, particularly in regions with thin soft tissue coverage, and underscores the importance of long‐term follow‐up.

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Publication Details

Journal
Oral Science International
Published
2026-02-24
DOI
https://doi.org/10.1002/osi2.70040
Primary Topic
Surgical Sutures and Adhesives
Type
article
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article

Delayed Inflammatory Foreign Body Reaction to PLLA After Genioplasty: A Case Report

Kamichika Hayashi, Shuji Yoshida, Kazuki MORIMOTO, Akane Ogiwara et al.
Oral Science International
Surgical Sutures and Adhesives
article

Delayed Inflammatory Foreign Body Reaction to PLLA After Genioplasty: A Case Report

Kamichika Hayashi, Shuji Yoshida, Kazuki MORIMOTO, Akane Ogiwara, Satoki Nshimura, Akira Watanabe
article en

Abstract

ABSTRACT Resorbable plates are widely used in maxillofacial surgery; however, delayed inflammatory foreign body reactions have occasionally been reported. We describe a case of a delayed inflammatory foreign body reaction to poly‐L‐lactic acid (PLLA) resorbable plates following genioplasty. An 18‐year‐old woman underwent genioplasty using PLLA resorbable plates and screws. Approximately 2 years after surgery, she developed progressive swelling and tenderness in the chin region. Computed tomography (CT) revealed localized bone resorption around the fixation device. Surgical removal of the degraded plate remnants, sequestrum, and surrounding inflammatory tissue was performed. Histopathological examination demonstrated granulation tissue containing PLLA fragments with a foreign body giant cell reaction. The postoperative course was uneventful, and bone regeneration was confirmed 1 year after removal. This case highlights that delayed inflammatory foreign body reactions to PLLA plates can occur years after genioplasty, particularly in regions with thin soft tissue coverage, and underscores the importance of long‐term follow‐up.

Oral Science InternationalVol. 23(2)
Tokyo Dental College (JP)
Openalex Percentile: Top 30%
Surgical Sutures and Adhesives
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