Risk of HSV-2 Acquisition Among Women with Bacterial Vaginosis: Systematic Review and Meta-Analysis
This systematic review with meta-analysis indicates that bacterial vaginosis is associated with a significantly increased risk (91% unadjusted, 85% adjusted) of herpes simplex virus 2 acquisition, indicating that bacterial vaginosis treatment may reduce herpes simplex virus 2 acquisition. A notable limitation of these findings is the relatively small number of studies eligible for inclusion in this systematic review and meta-analysis.
Authors
- Christina Farr Zuend (ORCID: https://orcid.org/0009-0001-4165-6909)
- Alexis E. Heath (ORCID: https://orcid.org/0009-0002-3969-4938)
- Taylor N. Whitt
- Douglas K. Brubaker
- D’Atra J. Hill
Institutions
- University Hospitals of Cleveland (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Viruses
- Published
- 2026-03-07
- DOI
- https://doi.org/10.3390/v18030330
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Case Western Reserve University