Iron concentration in the ventral pallidum of chronic migraine with medication-overuse headache

The reduced iron in subcortical nuclei, especially the VeP, relates to analgesic excessive use and relapse in MOH. This insight enhances our understanding of MOH's neurobiological basis and supports the potential development of QSM-based biomarkers for relapse risk prediction.

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Publication Details

Journal
The Journal of Headache and Pain
Published
2026-03-07
DOI
https://doi.org/10.1186/s10194-026-02321-2
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Iron concentration in the ventral pallidum of chronic migraine with medication-overuse headache

Kaicheng Li, Xiao Luo, Xiao Wu, P. Huang et al.
The Journal of Headache and Pain
Migraine and Headache Studies
article

Iron concentration in the ventral pallidum of chronic migraine with medication-overuse headache

Kaicheng Li, Xiao Luo, Xiao Wu, P. Huang, Fangling Zhao, Jiahui He, Jingxin Fu, Xiaojun Guan, Minming Zhang, Chao Wang, Xiaopei Xu, Kaiming Liu, Qingze Zeng, Mengting Zhou
article en

Abstract

The reduced iron in subcortical nuclei, especially the VeP, relates to analgesic excessive use and relapse in MOH. This insight enhances our understanding of MOH's neurobiological basis and supports the potential development of QSM-based biomarkers for relapse risk prediction.

The Journal of Headache and Pain
Hangzhou Hospital of Traditional Chinese Medicine (CN), Second Affiliated Hospital of Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 38%
Migraine and Headache Studies
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