Genebody specific epigenomic reprogramming of transcriptome promotes immune evasion in oropharyngeal cancer patients in North-Eastern India
These key alterations within tumour cells might effectively modulate the immune dynamics, leading to immune evasion by oropharyngeal malignant cells. The findings offer deep understanding of OPSCC and suggests novel immunotherapeutic targets, for the treatment of this challenging disease.
Authors
- Lastborn Marthong
- Subrata Patra
- Indranil Bagchi
- Neizekhotuo Brian Shunyu (ORCID: https://orcid.org/0000-0001-7667-662X)
- Srimoyee Ghosh
- Sahana Ghosh
Institutions
- North Eastern Hill University (IN)
- North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (IN)
- National Institute of Biomedical Genomics (IN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2026-03-08
- DOI
- https://doi.org/10.1186/s13148-026-02088-y
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00