Gallbladder tuberculosis as an incidental calcified mass in an elderly male: a case report

Gallbladder tuberculosis (GBT) is exceptionally rare and may closely mimic gallbladder carcinoma. We report a 71-year-old male with a history of successfully treated pulmonary tuberculosis who was asymptomatic and incidentally found on screening ultrasonography to have a calcified mass at the gallbladder fundus. Contrast-enhanced computed tomography (CT) demonstrated a 2 × 4 cm calcified fundal lesion with focal wall thickening, raising strong suspicion of malignancy. Laparoscopic cholecystectomy with intraoperative frozen section was performed. Despite severe inflammatory adhesions suggestive of invasive cancer, frozen section and final histopathology confirmed caseating granulomatous inflammation consistent with GBT, and surgery was limited to simple cholecystectomy. The postoperative course was uneventful, and the patient was referred for antituberculous therapy. GBT should be considered in the differential diagnosis of calcified gallbladder masses to avoid overtreatment.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2026-02-12
DOI
https://doi.org/10.1093/jscr/rjag123
Primary Topic
Diagnosis and treatment of tuberculosis
Type
article
Field-Weighted Citation Impact
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article

Gallbladder tuberculosis as an incidental calcified mass in an elderly male: a case report

Phuoc Thanh Bui, H Tran, Kim H Nguyen, Thanh P C Nguyen
Journal of Surgical Case Reports
Diagnosis and treatment of tuberculosis
article

Gallbladder tuberculosis as an incidental calcified mass in an elderly male: a case report

Phuoc Thanh Bui, H Tran, Kim H Nguyen, Thanh P C Nguyen
article en

Abstract

Gallbladder tuberculosis (GBT) is exceptionally rare and may closely mimic gallbladder carcinoma. We report a 71-year-old male with a history of successfully treated pulmonary tuberculosis who was asymptomatic and incidentally found on screening ultrasonography to have a calcified mass at the gallbladder fundus. Contrast-enhanced computed tomography (CT) demonstrated a 2 × 4 cm calcified fundal lesion with focal wall thickening, raising strong suspicion of malignancy. Laparoscopic cholecystectomy with intraoperative frozen section was performed. Despite severe inflammatory adhesions suggestive of invasive cancer, frozen section and final histopathology confirmed caseating granulomatous inflammation consistent with GBT, and surgery was limited to simple cholecystectomy. The postoperative course was uneventful, and the patient was referred for antituberculous therapy. GBT should be considered in the differential diagnosis of calcified gallbladder masses to avoid overtreatment.

Journal of Surgical Case ReportsVol. 2026(3)
TH Bingen University of Applied Sciences (DE), Pham Ngoc Thach University of Medicine (VN), Hotel Dieu Hospital (CA), University of Medicine and Pharmacy at Ho Chi Minh City (VN)
Good health and well-being
Openalex Percentile: Top 30%
Diagnosis and treatment of tuberculosis
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