Ultrasound, PET/CT or temporal artery biopsy for giant cell arteritis? A prospective diagnostic accuracy study (the GAME‐study)

Ultrasound had high diagnostic accuracy for GCA, supporting this as the first imaging modality in suspected GCA. 2-[<sup>18</sup>F]FDG PET/CT combined a high diagnostic accuracy with fewer inconclusive results, suggesting it may be used for second-line testing when ultrasound is inconclusive, reserving TAB for third-line testing. A fast-track setup may facilitate efficient diagnostics.

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Publication Details

Journal
Acta Ophthalmologica
Published
2026-03-07
DOI
https://doi.org/10.1111/aos.70114
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Ultrasound, PET/CT or temporal artery biopsy for giant cell arteritis? A prospective diagnostic accuracy study (the GAME‐study)

Y Subhi, Viktoria Fana, Oliver Niels Klefter, U. Møller Døhn et al.
Acta Ophthalmologica
Vasculitis and related conditions
article

Ultrasound, PET/CT or temporal artery biopsy for giant cell arteritis? A prospective diagnostic accuracy study (the GAME‐study)

Y Subhi, Viktoria Fana, Oliver Niels Klefter, U. Møller Døhn, Lene Terslev, M. Scharling Jensen, Michael Stormly Hansen, Anne Katrine Wiencke, Steffen Hamann, Steffen Heegaard, Jane M. Brittain
article en

Abstract

Ultrasound had high diagnostic accuracy for GCA, supporting this as the first imaging modality in suspected GCA. 2-[<sup>18</sup>F]FDG PET/CT combined a high diagnostic accuracy with fewer inconclusive results, suggesting it may be used for second-line testing when ultrasound is inconclusive, reserving TAB for third-line testing. A fast-track setup may facilitate efficient diagnostics.

Acta Ophthalmologica
University of Copenhagen (DK), University of Southern Denmark (DK), Bispebjerg Hospital (DK), Rigshospitalet (DK), Fondation de Rothschild (FR)
Openalex Percentile: Top 30%
Vasculitis and related conditions
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Ultrasound, PET/CT or temporal artery biopsy for giant cell arteritis? A prospective diagnostic accuracy study (the GAME‐study) — Y Subhi, Viktoria Fana, et al. · Acta Ophthalmologica (2026) | TGRS Research Map | TGRS