Win statistics applied to registry-based randomized clinical trials

Win statistics offer an alternative approach to traditional survival analysis by harnessing multiple events hierarchically by clinical importance. Win statistics also offer the potential to evaluate a broader range of clinical endpoints, providing a more rounded perspective of treatment efficacy, an important consideration when designing future randomized controlled trials. This is the first multi-registry-based controlled trial reanalysis using win statistics.

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Publication Details

Journal
Trials
Published
2026-03-07
DOI
https://doi.org/10.1186/s13063-026-09598-3
Primary Topic
Statistical Methods in Clinical Trials
Type
article
Field-Weighted Citation Impact
0.00
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article

Win statistics applied to registry-based randomized clinical trials

Robin Hofmann, Rebecca Tremain Rylance, Stefan James, Moman A. Mohammad et al.
Trials
Statistical Methods in Clinical Trials
article

Win statistics applied to registry-based randomized clinical trials

Robin Hofmann, Rebecca Tremain Rylance, Stefan James, Moman A. Mohammad, Philippe Wagner, Ole Fröbert, Matthias Götberg, David Erlinge
article en

Abstract

Win statistics offer an alternative approach to traditional survival analysis by harnessing multiple events hierarchically by clinical importance. Win statistics also offer the potential to evaluate a broader range of clinical endpoints, providing a more rounded perspective of treatment efficacy, an important consideration when designing future randomized controlled trials. This is the first multi-registry-based controlled trial reanalysis using win statistics.

Trials
Uppsala University (SE), Lund University (SE), Aarhus University (DK), Örebro University (SE), Karolinska Institutet (SE), Stockholm South General Hospital (SE), Skåne University Hospital (SE)
Openalex Percentile: Top 35%
Statistical Methods in Clinical Trials
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Win statistics applied to registry-based randomized clinical trials — Robin Hofmann, Rebecca Tremain Rylance, et al. · Trials (2026) | TGRS Research Map | TGRS