Which calcium preparation should we use in paediatric resuscitation? A comprehensive review of basic physiology, pharmacokinetics, and clinical evidence

The selection of a calcium preparation must be conditional and context-dependent. We recommend reserving CaCl₂ for central venous administration in volume-restricted or extreme emergent settings, whilst CaGN is the preferred choice for peripheral line administration or routine maintenance due to its superior safety profile.

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Publication Details

Journal
Journal of Anesthesia Analgesia and Critical Care
Published
2026-03-07
DOI
https://doi.org/10.1186/s44158-026-00369-9
Primary Topic
Poisoning and overdose treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Which calcium preparation should we use in paediatric resuscitation? A comprehensive review of basic physiology, pharmacokinetics, and clinical evidence

Constantinos Kanaris, Anna Camporesi, Swathy Subhash
Journal of Anesthesia Analgesia and Critical Care
Poisoning and overdose treatments
article

Which calcium preparation should we use in paediatric resuscitation? A comprehensive review of basic physiology, pharmacokinetics, and clinical evidence

Constantinos Kanaris, Anna Camporesi, Swathy Subhash
article en

Abstract

The selection of a calcium preparation must be conditional and context-dependent. We recommend reserving CaCl₂ for central venous administration in volume-restricted or extreme emergent settings, whilst CaGN is the preferred choice for peripheral line administration or routine maintenance due to its superior safety profile.

Journal of Anesthesia Analgesia and Critical Care
Queen Mary University of London (GB), University of Nicosia (CY), Cambridge University Hospitals NHS Foundation Trust (GB), Manchester University NHS Foundation Trust (GB), Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
Zero hunger
Openalex Percentile: Top 34%
Poisoning and overdose treatments
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