Fluoroquinolones and the risk of panic attacks: a systematic review and disproportionality analysis using individual case safety reports from the FDA Adverse Event Reporting System (FAERS) database
The findings suggest an association between fluoroquinolones and increased risk of panic attacks, underscoring the need for validation through pharmacoepidemiological studies. Due to reliance on spontaneous reports, causal relationships cannot be determined for clinical recommendations. These results offer insights for research on CNS safety profiles of fluoroquinolones.
Authors
- Hugues Sampasa‐Kanyinga (ORCID: https://orcid.org/0000-0002-7195-8086)
- Flory Tsobo Muanda (ORCID: https://orcid.org/0000-0003-4682-6564)
- Mohammad Ali Omrani (ORCID: https://orcid.org/0000-0001-6847-0699)
- Bala Swetha Baskaran
- Manroop Sidhu
- Niaz Chalabianloo
- Manik Chhabra
- Keeirah Hiertika Raguram
Institutions
- Western University (CA)
- Lawson Health Research Institute (CA)
- Children's Hospital of Eastern Ontario (CA)
- International Council for the Exploration of the Sea (DK)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2026-02-23
- DOI
- https://doi.org/10.1093/jac/dkag083
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00