Harnessing Platelet-derived factors to reactivate Nucleus Pulposus cells in Intervertebral Disc Regeneration

In conclusion, PL supports the maintenance of a progenitor state in NP cells and may contribute to the regeneration of damaged IVD tissue by activating resident quiescent stem/progenitor cells within the disc.

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Publication Details

Journal
Regenerative Therapy
Published
2026-03-07
DOI
https://doi.org/10.1016/j.reth.2026.101082
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
Field-Weighted Citation Impact
0.00
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article

Harnessing Platelet-derived factors to reactivate Nucleus Pulposus cells in Intervertebral Disc Regeneration

M. Nardini, C. Gentili, R. Cancedda, P. Ferrari et al.
Regenerative Therapy
Spine and Intervertebral Disc Pathology
article

Harnessing Platelet-derived factors to reactivate Nucleus Pulposus cells in Intervertebral Disc Regeneration

M. Nardini, C. Gentili, R. Cancedda, P. Ferrari, E. Giannarelli, A. Muraglia, A. Zanirato, M. Formica, G. Filaci, M. Mastrogiacomo
article en

Abstract

In conclusion, PL supports the maintenance of a progenitor state in NP cells and may contribute to the regeneration of damaged IVD tissue by activating resident quiescent stem/progenitor cells within the disc.

Regenerative TherapyVol. 32
Ospedale Policlinico San Martino (IT), University of Genoa (IT)
Zero hunger
Openalex Percentile: Top 31%
Spine and Intervertebral Disc Pathology
DOIOpen Access PDFOpenAlex
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