Association of glucagon‐like peptide‐1 receptor agonist use with clinical outcomes in patients with rheumatoid arthritis and type 2 diabetes

In patients with rheumatoid arthritis and type 2 diabetes, GLP-1 RA therapy was associated with 32% lower mortality, 11% fewer kidney events, and 8% fewer hospitalizations vs DPP-4is. These findings support GLP-1 RAs as a promising therapeutic option for this high-risk population.

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Publication Details

Journal
Journal of Diabetes Investigation
Published
2026-03-07
DOI
https://doi.org/10.1111/jdi.70281
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of glucagon‐like peptide‐1 receptor agonist use with clinical outcomes in patients with rheumatoid arthritis and type 2 diabetes

Yuting Yu, Ying Chun Lee, Wen-Hui Hsieh, Ming-Hsien Tsai et al.
Journal of Diabetes Investigation
Rheumatoid Arthritis Research and Therapies
article

Association of glucagon‐like peptide‐1 receptor agonist use with clinical outcomes in patients with rheumatoid arthritis and type 2 diabetes

Yuting Yu, Ying Chun Lee, Wen-Hui Hsieh, Ming-Hsien Tsai, Yu-Wei Fang
article en

Abstract

In patients with rheumatoid arthritis and type 2 diabetes, GLP-1 RA therapy was associated with 32% lower mortality, 11% fewer kidney events, and 8% fewer hospitalizations vs DPP-4is. These findings support GLP-1 RAs as a promising therapeutic option for this high-risk population.

Journal of Diabetes Investigation
Fu Jen Catholic University (TW), Landseed Hospital (TW), Memorial Hospital (US)
Good health and well-being
Openalex Percentile: Top 29%
Rheumatoid Arthritis Research and Therapies
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