CEBPB-high dormant tumor cells drive immune evasion via S100A8 orchestrated tumor-associated macrophages reprogramming

Our study demonstrate a mechanistic link between tumor dormancy and immune evasion, highlighting the CEBPB-S100A8 axis as a promising therapeutic target to potentiate ICB efficacy in TNBC.

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Publication Details

Journal
Theranostics
Published
2026-02-26
DOI
https://doi.org/10.7150/thno.124789
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

CEBPB-high dormant tumor cells drive immune evasion via S100A8 orchestrated tumor-associated macrophages reprogramming

Huilan Su, Jin Bai, Shunxi Wang, Yang Dong et al.
Theranostics
Immune cells in cancer
article

CEBPB-high dormant tumor cells drive immune evasion via S100A8 orchestrated tumor-associated macrophages reprogramming

Huilan Su, Jin Bai, Shunxi Wang, Yang Dong, Yong Gao
article en

Abstract

Our study demonstrate a mechanistic link between tumor dormancy and immune evasion, highlighting the CEBPB-S100A8 axis as a promising therapeutic target to potentiate ICB efficacy in TNBC.

TheranosticsVol. 16(9)
Army Medical University (CN), Daping Hospital (CN), Chongqing 2D Materials Institute (China) (CN), Shanghai East Hospital (CN), Southwest Hospital (CN)
Zero hunger
Openalex Percentile: Top 31%
Immune cells in cancer
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