Efficacy and Safety of Deferiprone for Parkinson’s Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Deferiprone shows potential in slowing motor symptom progression in Parkinson's disease, although its impact on brain iron levels remains inconclusive. Further large-scale, long-term studies are warranted to establish its clinical efficacy and safety.

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Publication Details

Journal
Clinical Neuropharmacology
Published
2026-01-29
DOI
https://doi.org/10.1097/wnf.0000000000000669
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
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article

Efficacy and Safety of Deferiprone for Parkinson’s Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials

R Rohan, Sridevi Ravi, Dhruv Jayeshkumar Shah, Deekshitha Alla et al.
Clinical Neuropharmacology
Parkinson's Disease Mechanisms and Treatments
article

Efficacy and Safety of Deferiprone for Parkinson’s Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials

R Rohan, Sridevi Ravi, Dhruv Jayeshkumar Shah, Deekshitha Alla, Soujanya Tirupati, Rakshna Ramsundar, Aradhya Singh, Sai Lokesh Moraboina, Chandana Priya Digumurthy, Jashika Mellamput, Mrudula Alla
article en

Abstract

Deferiprone shows potential in slowing motor symptom progression in Parkinson's disease, although its impact on brain iron levels remains inconclusive. Further large-scale, long-term studies are warranted to establish its clinical efficacy and safety.

Clinical NeuropharmacologyVol. 49(2)
Andhra University (IN), Trinity Health (US), Massachusetts College of Pharmacy and Health Sciences (US), Sri Ramachandra Institute of Higher Education and Research (IN), Windsor University School of Medicine (KN), Narayana Dental College and Hospital (IN), Apollo Institute of Medical Sciences & Research (IN), JSS Medical College and Hospital (IN)
Good health and well-being
Openalex Percentile: Top 38%
Parkinson's Disease Mechanisms and Treatments
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Efficacy and Safety of Deferiprone for Parkinson’s Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials — R Rohan, Sridevi Ravi, et al. · Clinical Neuropharmacology (2026) | TGRS Research Map | TGRS