Synthesis of Ethyl 2-Amino-6-hydroxy-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate and Ethyl 6-(Acetyloxy)-2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
An effective one-step synthetic procedure for preparation of hydroxylated analogues of ethyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate as novel promising multifunctional building blocks for drug discovery based on the Gewald procedure was developed.
Authors
- Georgiy G. Yakovenko
- Sergiy V. Vlasov (ORCID: https://orcid.org/0000-0001-5568-8357)
- Hanna Severina
- Andrii R. Khairulin
- Andrii Yu. Myshastyi
Institutions
- Taras Shevchenko National University of Kyiv (UA)
- H.S. Skovoroda Kharkiv National Pedagogical University (UA)
- National University of Pharmacy (UA)
- Enamine (Ukraine) (UA)
Publication Details
- Journal
- Molbank
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3390/m2144
- Primary Topic
- Synthesis and Characterization of Pyrroles
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Enamine