Cultryx: Precision Diagnostic Stewardship for Blood Cultures Using Machine Learning

Cultryx, a machine learning model for blood culture stewardship, outperforms standard clinical heuristics in predicting bacteremia. This approach could reduce culture utilization by over 26% while preserving pathogen detection, conserving diagnostic resources, reducing unnecessary antibiotic exposure, and elevating patient safety.

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Publication Details

Journal
medRxiv
Published
2026-03-04
DOI
https://doi.org/10.64898/2026.02.27.26347214
Primary Topic
Bacterial Identification and Susceptibility Testing
Type
article
Field-Weighted Citation Impact
0.00

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article

Cultryx: Precision Diagnostic Stewardship for Blood Cultures Using Machine Learning

Kameron Collin Black, P. Stephen, Fatemeh Amrollahi, Fateme Nateghi Haredasht et al.
medRxiv
Bacterial Identification and Susceptibility Testing
article

Cultryx: Precision Diagnostic Stewardship for Blood Cultures Using Machine Learning

Kameron Collin Black, P. Stephen, Fatemeh Amrollahi, Fateme Nateghi Haredasht, Aydin Zahedivash, Niaz Banaei, Amy Chang, Stanley C. Deresinski, Manoj Maddali, Steven Asch, Wenyuan Chen, Mary Kane Goldstein, Jonathan H Chen, Nicholas P Marshall
article en

Abstract

Cultryx, a machine learning model for blood culture stewardship, outperforms standard clinical heuristics in predicting bacteremia. This approach could reduce culture utilization by over 26% while preserving pathogen detection, conserving diagnostic resources, reducing unnecessary antibiotic exposure, and elevating patient safety.

medRxiv
Palo Alto University (US), Stanford Health Care (US), Stanford Medicine (US), Stanford University (US)
National Institutes of Health, Stanford Bio-X, National Institute of Allergy and Infectious Diseases, National Center for Advancing Translational Sciences, Stanford Maternal and Child Health Research Institute
Openalex Percentile: Top 31%
Bacterial Identification and Susceptibility Testing
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