FFAR4 negatively regulates colorectal cancer growth via blocking oxidative phosphorylation
FFAR4 suppresses CRC growth by modulating mitochondrial function and cellular metabolism, supporting its potential as a diagnostic biomarker and therapeutic strategy for CRC.
Authors
- Lengyun Wei (ORCID: https://orcid.org/0000-0001-5985-0868)
- Qun Wang (ORCID: https://orcid.org/0000-0001-7929-7692)
- Fan Fan (ORCID: https://orcid.org/0000-0003-1463-3610)
- Benfei Hu
- Wei Wei
- Pengpeng Long
- Chenfeng Liu
- Dashuai Li
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2026-03-05
- DOI
- https://doi.org/10.1186/s12967-026-07942-4
- Primary Topic
- Aldose Reductase and Taurine
- Type
- article
- Field-Weighted Citation Impact
- 0.00