Voriconazole as a Secondary Prophylaxis for Invasive Fungal Infections in Allogeneic Hematopoietic Stem Cell Transplantation: Real-world Evidence From a Major Transplantation Center in Taiwan

Transient fluctuations in voriconazole levels occur after allo-HSCT, independent of most clinical factors. These subtherapeutic exposures did not significantly affect the incidence of breakthrough IFIs in this cohort. Larger prospective studies are warranted to further investigate the clinical impact.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2026-02-26
DOI
https://doi.org/10.1093/ofid/ofag101
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
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article

Voriconazole as a Secondary Prophylaxis for Invasive Fungal Infections in Allogeneic Hematopoietic Stem Cell Transplantation: Real-world Evidence From a Major Transplantation Center in Taiwan

C. -C. Lin, Xiu-Wen Liao, Lin Fh, Yee-Chun Chen et al.
Open Forum Infectious Diseases
Antifungal resistance and susceptibility
article

Voriconazole as a Secondary Prophylaxis for Invasive Fungal Infections in Allogeneic Hematopoietic Stem Cell Transplantation: Real-world Evidence From a Major Transplantation Center in Taiwan

C. -C. Lin, Xiu-Wen Liao, Lin Fh, Yee-Chun Chen, Shu-Wen Lin, Shang-Ju Wu, Xavier Cheng-Hong Tsai, Chih-Ning Cheng, Zong-Da Hsieh, Yu-Wen Wang, Ching-Hua Kuo, Jiun-Da Huang
article en

Abstract

Transient fluctuations in voriconazole levels occur after allo-HSCT, independent of most clinical factors. These subtherapeutic exposures did not significantly affect the incidence of breakthrough IFIs in this cohort. Larger prospective studies are warranted to further investigate the clinical impact.

Open Forum Infectious DiseasesVol. 13(3)
National Taiwan University (TW), National Taiwan University Hospital (TW), National Chengchi University (TW), National Taipei University (TW)
Good health and well-being
Openalex Percentile: Top 34%
Antifungal resistance and susceptibility
DOIOpen Access PDFOpenAlex
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