Unveiling the Secrets of Probiotics: Transforming Oral Health from Within

Abstract Oral diseases, including dental caries, periodontal diseases, and halitosis, are prevalent worldwide and significantly impact public health. Traditional preventive and therapeutic approaches have limitations, leading to increased interest in alternative strategies. Probiotics, live microorganisms that confer health benefits to the host, have emerged as a promising adjunct in oral health management. This review aims to explore the role of probiotics in maintaining and improving oral health. A comprehensive literature search was conducted across multiple databases, including PubMed, Scopus, and Web of Science, to identify relevant studies published between January 2000 and April 2023. Inclusion criteria encompassed human clinical trials assessing the effects of probiotic interventions on oral health parameters. Studies focusing on dental caries, periodontal diseases, and halitosis were prioritized. The findings suggest that specific probiotic strains, such as Lactobacillus and Bifidobacterium, can modulate the oral microbiota, suppress pathogenic bacteria, and enhance the host's immune response. Probiotic interventions have demonstrated efficacy in reducing the incidence of dental caries, alleviating symptoms of periodontal diseases, and mitigating halitosis. However, variability in study designs, probiotic strains used, dosages, and delivery methods necessitates cautious interpretation of results. In conclusion, probiotics represent a viable adjunctive therapy in oral health management. Standardization of probiotic formulations, dosages, and treatment protocols, along with long-term clinical studies, are essential to establish definitive guidelines for their use in oral health care.

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Publication Details

Journal
European Dental Research and Biomaterials Journal
Published
2026-03-05
DOI
https://doi.org/10.1055/s-0046-1817787
Primary Topic
Oral microbiology and periodontitis research
Type
article
Field-Weighted Citation Impact
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article

Unveiling the Secrets of Probiotics: Transforming Oral Health from Within

Kambiz Eftekhari, Armen Malekiantaghi, Emil Malekiantaghi
European Dental Research and Biomaterials Journal
Oral microbiology and periodontitis research
article

Unveiling the Secrets of Probiotics: Transforming Oral Health from Within

Kambiz Eftekhari, Armen Malekiantaghi, Emil Malekiantaghi
article en

Abstract

Abstract Oral diseases, including dental caries, periodontal diseases, and halitosis, are prevalent worldwide and significantly impact public health. Traditional preventive and therapeutic approaches have limitations, leading to increased interest in alternative strategies. Probiotics, live microorganisms that confer health benefits to the host, have emerged as a promising adjunct in oral health management. This review aims to explore the role of probiotics in maintaining and improving oral health. A comprehensive literature search was conducted across multiple databases, including PubMed, Scopus, and Web of Science, to identify relevant studies published between January 2000 and April 2023. Inclusion criteria encompassed human clinical trials assessing the effects of probiotic interventions on oral health parameters. Studies focusing on dental caries, periodontal diseases, and halitosis were prioritized. The findings suggest that specific probiotic strains, such as Lactobacillus and Bifidobacterium, can modulate the oral microbiota, suppress pathogenic bacteria, and enhance the host's immune response. Probiotic interventions have demonstrated efficacy in reducing the incidence of dental caries, alleviating symptoms of periodontal diseases, and mitigating halitosis. However, variability in study designs, probiotic strains used, dosages, and delivery methods necessitates cautious interpretation of results. In conclusion, probiotics represent a viable adjunctive therapy in oral health management. Standardization of probiotic formulations, dosages, and treatment protocols, along with long-term clinical studies, are essential to establish definitive guidelines for their use in oral health care.

European Dental Research and Biomaterials Journal
Children's Medical Center (IR), Yerevan State Medical University (AM), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 34%
Oral microbiology and periodontitis research
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