Clinical characteristics, effectiveness, safety, and predictors of PASI75/90 responses to IL-17 biologics in psoriasis involving special sites: a large real-world cohort study revealing treatment response heterogeneity

Overall, IL-17 inhibitors show substantial efficacy and a favorable safety profile for psoriasis in special sites, with treatment response variability influenced primarily by baseline clinical characteristics such as BMI and disease severity indices.

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Publication Details

Journal
Journal of Dermatological Treatment
Published
2026-03-04
DOI
https://doi.org/10.1080/09546634.2026.2633794
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical characteristics, effectiveness, safety, and predictors of PASI75/90 responses to IL-17 biologics in psoriasis involving special sites: a large real-world cohort study revealing treatment response heterogeneity

Xiaohua Tao, Xinglong Xiong, Fengming Hu, Lihua Zhang et al.
Journal of Dermatological Treatment
Psoriasis: Treatment and Pathogenesis
article

Clinical characteristics, effectiveness, safety, and predictors of PASI75/90 responses to IL-17 biologics in psoriasis involving special sites: a large real-world cohort study revealing treatment response heterogeneity

Xiaohua Tao, Xinglong Xiong, Fengming Hu, Lihua Zhang, Yujie Lai
article en

Abstract

Overall, IL-17 inhibitors show substantial efficacy and a favorable safety profile for psoriasis in special sites, with treatment response variability influenced primarily by baseline clinical characteristics such as BMI and disease severity indices.

Journal of Dermatological TreatmentVol. 37(1)
Nanchang University (CN), Second Affiliated Hospital of Nanchang University (CN), Gannan Medical University (CN), Jiangxi Chest Hospital (CN), First Affiliated Hospital of Nanchang University (CN)
Good health and well-being
Openalex Percentile: Top 32%
Psoriasis: Treatment and Pathogenesis
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