Clinical, laboratory, and histopathological characteristics of pediatric lupus nephritis: a retrospective study in a national referral center in Mexico

This study represents one of the largest pediatric LN cohorts reported from Mexico. Proliferative forms were associated with greater inflammatory activity and impaired renal function at diagnosis. Hypoalbuminemia emerged as a simple and accessible biomarker for early risk stratification of severe renal outcomes.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2026-03-05
DOI
https://doi.org/10.3389/fped.2026.1743610
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
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article

Clinical, laboratory, and histopathological characteristics of pediatric lupus nephritis: a retrospective study in a national referral center in Mexico

Héctor Menchaca-Aguayo, Enrique Faugier-Fuentes, Abril Bernabe-Jiménez, Karla Chacón-Abril
Frontiers in Pediatrics
Systemic Lupus Erythematosus Research
article

Clinical, laboratory, and histopathological characteristics of pediatric lupus nephritis: a retrospective study in a national referral center in Mexico

Héctor Menchaca-Aguayo, Enrique Faugier-Fuentes, Abril Bernabe-Jiménez, Karla Chacón-Abril
article en

Abstract

This study represents one of the largest pediatric LN cohorts reported from Mexico. Proliferative forms were associated with greater inflammatory activity and impaired renal function at diagnosis. Hypoalbuminemia emerged as a simple and accessible biomarker for early risk stratification of severe renal outcomes.

Frontiers in PediatricsVol. 14
Hospital Universitario San Agustín (ES), Hospital Infantil de México Federico Gómez (MX), Instituto Nacional de Enfermedades Respiratorias (MX)
Good health and well-being
Openalex Percentile: Top 31%
Systemic Lupus Erythematosus Research
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